E-commerce sellers listing cosmetics, skincare, hair care, or personal care products

MoCRA Cosmetics Compliance for E-Commerce Sellers (2026)

Updated March 29, 2026By Prodovo Labs Compliance Team

The Modernization of Cosmetics Regulation Act (MoCRA) is the biggest change to U.S. cosmetics law in 86 years. If you sell skincare, makeup, hair care, soap, or any product marketed for cleansing or beautifying, these rules now apply to you — including small sellers and private label brands. Here's what you actually need to do.

Quick Answer

Under MoCRA, cosmetics sellers must register their manufacturing facility with the FDA, list each product in the FDA system, maintain adverse event records, ensure proper labeling (including fragrance allergens by 2027), and follow GMP guidelines. Small businesses with under $1M in annual sales get some exemptions but still must register and list products.

Why You're Probably Here

Amazon asked for FDA cosmetics facility registration or product listing number

Amazon is increasingly enforcing MoCRA requirements. Sellers without FDA registration numbers may face listing suppression or removal for cosmetics categories.

You launched a private label skincare or beauty brand and aren't sure what's required

Private label sellers are the "responsible person" under MoCRA — not the contract manufacturer. You are legally responsible for registration, listing, and adverse event reporting.

You received a customer complaint about a reaction to your product

Under MoCRA, serious adverse events must be reported to the FDA within 15 business days. Failure to report can result in enforcement action.

What Matters Most

You are the "responsible person" — not your manufacturer

MoCRA makes the brand owner the responsible person. Even if a contract manufacturer makes your product, you are legally responsible for registration, listing, labeling, and adverse event reporting.

Small business exemptions exist but are limited

Businesses with under $1M in average annual cosmetics sales are exempt from some GMP and recordkeeping requirements, but must still register facilities, list products, and report serious adverse events.

Facility registration and product listing are free

Both are done through the FDA's Cosmetics Direct portal at no cost. Don't pay a third-party company hundreds of dollars to "file your FDA registration" — it's a simple online form.

Requirements

FDA Facility Registration

Required

MoCRA Section 607

Every facility that manufactures or processes cosmetics for U.S. distribution must register with the FDA. This includes contract manufacturers and foreign facilities.

Why it applies: If you have products made for you (private label) or manufacture yourself, the production facility must be FDA-registered.

What this means for you: Your manufacturer needs to register with the FDA. If they're overseas, they still need to register. If they won't, that's a red flag. Registration is free and done online through the FDA's Cosmetics Direct portal.

Official source

Cosmetic Product Listing

Required

MoCRA Section 608

Each cosmetic product must be listed with the FDA, including ingredient lists and product categories.

Why it applies: Every product you sell — even variations like different shades or scents — needs to be listed in the FDA system.

What this means for you: You list each product through the FDA's Cosmetics Direct system. It's free but tedious — you need full ingredient lists and product categories for each SKU.

Adverse Event Reporting

Required

MoCRA Section 605

Serious adverse events (hospitalization, significant disability, birth defects) must be reported to the FDA within 15 business days of receiving the report.

Why it applies: As the "responsible person," the brand owner (you) must maintain records of all adverse event reports and report serious ones to the FDA.

What this means for you: If a customer emails you saying your face cream sent them to the ER, you have 15 business days to report it to the FDA. Keep records of all customer complaints about reactions.

Cosmetics Labeling Requirements

Required

21 CFR 701, FD&C Act 602

Cosmetics must list ingredients in descending order (INCI names), include warnings where applicable, and display the responsible person's name and address.

Why it applies: All cosmetics sold in the U.S. need proper labeling. MoCRA added new fragrance allergen disclosure requirements starting in 2027.

What this means for you: Your label needs an ingredient list (INCI names, not marketing names), your business name and address, net quantity, and any required warnings. Fragrance allergen listings become mandatory in 2027.

Good Manufacturing Practice (GMP)

Important

MoCRA Section 606

Cosmetics must be manufactured in accordance with good manufacturing practices. FDA is expected to finalize specific GMP rules for cosmetics.

Why it applies: GMP ensures products are consistently produced and controlled. FDA has proposed rules modeled on existing industry standards (ISO 22716).

What this means for you: Your manufacturer should follow ISO 22716 (cosmetics GMP). Ask for their GMP certification or audit results. If they can't provide any quality documentation, find a new manufacturer.

California Proposition 65

Important

Cal. Health & Safety Code 25249.6

Cosmetics containing Prop 65 listed chemicals (lead, titanium dioxide, certain fragrance chemicals) above safe harbor levels require California warnings.

Why it applies: Many cosmetics contain trace amounts of Prop 65-listed substances. Bounty hunter lawsuits targeting cosmetics are increasing.

What this means for you: If selling cosmetics to California, add Prop 65 warnings for products containing lead, titanium dioxide, or certain fragrance ingredients. Testing costs $200-$400 and protects against lawsuits.

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What Sellers Get Wrong

Assuming "cosmeceuticals" are exempt because they're marketed as skincare

Why sellers do this: Sellers think products with active ingredients like retinol or vitamin C are drugs, not cosmetics.

The reality: If your product is intended to beautify, cleanse, or alter appearance, it's a cosmetic under MoCRA — regardless of active ingredients. Some products may be both a drug and a cosmetic, which means double regulation.

Thinking your contract manufacturer handles all compliance

Why sellers do this: Sellers assume the manufacturer is responsible for FDA compliance.

The reality: The brand owner is the responsible person under MoCRA. Your manufacturer must register their facility, but you are responsible for product listing, labeling, and adverse event reporting.

Using marketing ingredient names instead of INCI names on labels

Why sellers do this: Sellers want labels to read well for consumers.

The reality: FDA requires INCI (International Nomenclature of Cosmetic Ingredients) names on ingredient lists. "Vitamin E" must be listed as "Tocopheryl Acetate" (or the specific form used).

Not keeping adverse event records because you've never had a complaint

Why sellers do this: Small sellers think adverse event reporting only applies to big brands.

The reality: You must maintain a system to receive, track, and report adverse events from day one. Even negative Amazon reviews describing skin reactions could qualify.

What Most Guides Won't Tell You

Check if your product is actually a drug, not just a cosmetic

Products claiming to treat acne, reduce wrinkles, provide sun protection, or promote hair growth are drugs under FDA law — even if marketed as skincare. Drugs have much stricter requirements (NDAs, OTC monographs).

Fragrance allergen disclosure is coming in 2027 — prepare now

MoCRA requires disclosure of specific fragrance allergens on labels by late 2027. If your products contain fragrance, start getting full allergen breakdowns from your fragrance supplier now to avoid a last-minute label redesign.

Soap is exempt from MoCRA — but most "soaps" aren't actually soap

True soap (alkali salts of fatty acids, marketed only for cleansing) is exempt. But if your "soap" contains synthetic detergents, or if you claim it moisturizes, deodorizes, or has any cosmetic benefit, it's a cosmetic under MoCRA.

PFAS bans are spreading fast

Multiple states have banned intentionally added PFAS in cosmetics (California, Maryland, others following). If your manufacturer uses PFAS-containing ingredients, you need to reformulate or face state enforcement.

What To Do Next

1

Confirm your manufacturer's FDA facility registration

Ask your manufacturer for their FDA facility registration number. If they don't have one, they need to register through FDA's Cosmetics Direct portal before you can sell.

2

List each product in the FDA Cosmetics Direct system

Create an account on the FDA's Cosmetics Direct portal and list every product you sell, including full ingredient lists in INCI format.

3

Audit your labels for compliance

Verify ingredient lists use INCI names in descending order, required warnings are present, your business name and address are displayed, and net quantity is correct.

4

Set up an adverse event tracking system

Create a process to monitor customer complaints (including Amazon reviews) for adverse events and report serious ones to FDA within 15 business days.

5

Run a Prodovo Labs scan for your specific product

Cosmetics requirements vary by product type (color cosmetics vs. skincare), target market (children's cosmetics have extra rules), and sales region. A scan identifies everything that applies.

Frequently Asked Questions

Does MoCRA apply to small sellers and private label brands?
Yes. MoCRA applies to anyone selling cosmetics in the U.S., regardless of size. Small businesses (under $1M annual cosmetics sales) get some GMP and recordkeeping exemptions, but must still register facilities, list products, and report serious adverse events.
Is my handmade soap exempt from MoCRA?
Only if it's true soap (alkali salts of fatty acids, marketed solely for cleansing). If your soap contains synthetic detergents, or if you claim it moisturizes, exfoliates, or has any cosmetic benefit beyond cleansing, it's a cosmetic and MoCRA applies.
How much does MoCRA compliance cost?
FDA facility registration and product listing are free. The main costs are label redesign ($200-$500 per SKU), Prop 65 testing ($200-$400), and potentially GMP audits ($1,000-$3,000). Most small sellers can achieve compliance for under $2,000 total.
What happens if I don't comply with MoCRA?
FDA can issue warning letters, seize products, or seek injunctions. More practically, Amazon and other marketplaces are beginning to require FDA registration numbers, so non-compliance may result in listing suppression.
Do I need to test my cosmetics?
MoCRA does not require mandatory pre-market testing for cosmetics (unlike drugs). However, you must ensure products are safe and properly labeled. Prop 65 testing is strongly recommended if selling to California.

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